Disease-gene associations mined from literature

Literature associating CREB1 and cerebellar hypoplasia

CREB1 [ENSP00000387699]

Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells; Belongs to the bZIP family.

Synonyms:  CREB1,  CREB1p,  hCREB1,  C9J276,  C9J4L5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM