Disease-gene associations mined from literature

Literature associating FUT2 and spontaneous ocular nystagmus

FUT2 [ENSP00000387498]

Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids . The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (PubMed:12692541, PubMed:8018146). Mediates interaction with intestinal microbiota influencing its composition (PubMed:21625510, PubMed:24733310, PubMed:22068912). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway . ECO:0000269|PubMed:22068912, ECO:0000269|PubMed:24733310,

Synonyms:  FUT2,  FUT2p,  hFUT2,  A8K2L2,  E7EW73 ...

Linkouts:  STRING  Pharos  UniProt