Disease-gene associations mined from literature

Literature associating ARTN and Hirschsprung's disease

ARTN [ENSP00000387435]

Neublastin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue; GDNF family ligands

Synonyms:  ARTN,  E9PIK2,  E9PLG3,  E9PN22,  Q5T4W7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM