Literature associating UBE4A and Crohn's disease
RING-type E3 ubiquitin transferase E4 A; Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates; Armadillo-like helical domain containing
Synonyms: UBE4A, UBE4Ap, hUBE4A, B7Z7P0, Q14139 ...