DISEASES

Disease-gene associations mined from literature

Literature associating NPPC and hypochondroplasia

NPPC [ENSP00000387159]

C-type natriuretic peptide; Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity); Endogenous ligands

Synonyms:  NPPC,  E5LCN7,  P23582,  CNP2,  E5LCN7p ...

Linkouts:  STRING  Pharos  UniProt