DISEASES

Disease-gene associations mined from literature

Literature associating STK16 and thymus cancer

STK16 [ENSP00000386928]

Myristoylated and palmitoylated serine/threonine-protein kinase; Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.

Synonyms:  STK16,  STK16p,  hSTK16,  A0A024R440,  B4DPS1 ...

Linkouts:  STRING  Pharos  UniProt