DISEASES

Disease-gene associations mined from literature

Literature associating FHL2 and rhabdomyosarcoma

FHL2 [ENSP00000386665]

Four and a half LIM domains protein 2; May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation; LIM domain containing

Synonyms:  FHL2,  FHL2p,  hFHL2,  C9J3S8,  E9PKF4 ...

Linkouts:  STRING  Pharos  UniProt