DISEASES

Disease-gene associations mined from literature

Literature associating ZC3H12D and diffuse large B-cell lymphoma

ZC3H12D [ENSP00000386616]

Zinc finger CCCH domain-containing protein 12D; May regulate cell growth likely by suppressing RB1 phosphorylation. May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages. Serve as a tumor suppressor in certain leukemia cells. Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation.

Synonyms:  ZC3H12D,  ZC3H12Dp,  hZC3H12D,  A2A288,  B7ZBA4 ...

Linkouts:  STRING  Pharos  UniProt