DISEASES

Disease-gene associations mined from literature

Literature associating APOPT1 and L-2-hydroxyglutaric aciduria

APOPT1 [ENSP00000386485]

Apoptogenic protein 1, mitochondrial; Plays a role in the regulation of apoptosis. Mediates mitochondria-induced cell death in vascular smooth muscle cells through the release of cytochrome c from mitochondria, followed by the activation of the caspase cascade.

Synonyms:  APOPT1,  APOPT1p,  hAPOPT1,  G3V4L6,  H0YJK3 ...

Linkouts:  STRING  Pharos  UniProt