DISEASES

Disease-gene associations mined from literature

Literature associating KCNS3 and generalized epilepsy with febrile seizures plus 4

KCNS3 [ENSP00000385968]

Potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1. Heterotetrameric channel activity formed with KCNB1 show increased current amplitude with the threshold for action potential activation shifted towards more negative values in hypoxic-treated pulmonary artery smooth muscle cells (By similarity).

Synonyms:  KCNS3,  KCNS3p,  hKCNS3,  C9J187,  Q9BQ31 ...

Linkouts:  STRING  Pharos  UniProt