DISEASES

Disease-gene associations mined from literature

Literature associating NAA60 and Scheuermann's disease

NAA60 [ENSP00000385903]

N(alpha)-acetyltransferase 60, NatF catalytic subunit; N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol. Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences; Belongs to the acetyltransferase family. NAA60 subfamily.

Synonyms:  NAA60,  NAA60p,  hNAA60,  I3L115,  I3L153 ...

Linkouts:  STRING  Pharos  UniProt