DISEASES

Disease-gene associations mined from literature

Literature associating TST and ethylmalonic encephalopathy

TST [ENSP00000385828]

Thiosulfate sulfurtransferase (rhodanese); Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity (By similarity). Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA.

Synonyms:  TST,  B1AH48,  Q16762,  B1AH48p,  hB1AH48 ...

Linkouts:  STRING  Pharos  UniProt