DISEASES

Disease-gene associations mined from literature

Literature associating WDR62 and primary autosomal recessive microcephaly

WDR62 [ENSP00000384792]

WD repeat-containing protein 62; Required for cerebral cortical development. Plays a role in neuronal proliferation and migration. Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication; WD repeat domain containing

Synonyms:  WDR62,  WDR62p,  hWDR62,  H7C3R4,  O43379 ...

Linkouts:  STRING  Pharos  UniProt  OMIM