DISEASES

Disease-gene associations mined from literature

SearchDownloadsAbout

Literature associating CTNNA2 and cerebellar hypoplasia

CTNNA2 [ENSP00000384638]

Catenin (cadherin-associated protein), alpha 2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation; Alpha catenins

Synonyms:  CTNNA2,  CTNNA2p,  hCTNNA2,  B8ZZE7,  B9A010 ...

Linkouts:  STRING  Pharos  UniProt

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.