Disease-gene associations mined from literature

Literature associating TFIP11 and dental caries

TFIP11 [ENSP00000384421]

Septin and tuftelin-interacting protein 1; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix; G-patch domain containing

Synonyms:  TFIP11,  TFIP11p,  hTFIP11,  A0A024R1I7,  B1AHQ3 ...

Linkouts:  STRING  Pharos  UniProt