DISEASES

Disease-gene associations mined from literature

Literature associating NCOR2 and acute promyelocytic leukemia

NCOR2 [ENSP00000384018]

Silencing mediator of retinoic acid and thyroid hormone receptor; Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival; Myb/SANT domain containing

Synonyms:  NCOR2,  NCOR2p,  hNCOR2,  A0A024RBS3,  C9J0Q5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM