DISEASES

Disease-gene associations mined from literature

Literature associating MASP2 and Chagas disease

MASP2 [ENSP00000383690]

Mannose-binding protein-associated serine protease 2; Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase; Sushi domain containing

Synonyms:  MASP2,  MASP2p,  hMASP2,  MASP2-001,  MASP2-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM