Disease-gene associations mined from literature

Literature associating MORC3 and childhood type dermatomyositis

MORC3 [ENSP00000383333]

Zinc finger CW-type coiled-coil domain protein 3; Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in vitro. May be required for influenza A transcription during viral infection; Zinc fingers CW-type

Synonyms:  MORC3,  MORC3p,  hMORC3,  A2RU29,  B4DHJ4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM