DISEASES

Disease-gene associations mined from literature

Literature associating USP25 and ARC syndrome

USP25 [ENSP00000383044]

Ubiquitin-specific-processing protease 25; Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains; Belongs to the peptidase C19 family.

Synonyms:  USP25,  USP25p,  hUSP25,  Q96B65,  Q9HA22 ...

Linkouts:  STRING  Pharos  UniProt