DISEASES

Disease-gene associations mined from literature

Literature associating CLDN8 and chromophobe renal cell carcinoma

CLDN8 [ENSP00000382783]

Claudin 8; Tight-junction protein required for paracellular chloride transport in the kidney. Mediates recruitment of CLDN4 to tight junction in the kidney. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Synonyms:  CLDN8,  CLDN8p,  hCLDN8,  P56748,  P56748p ...

Linkouts:  STRING  Pharos  UniProt