Literature associating ABCC1 and colon adenocarcinoma
ATP-binding cassette, sub-family C (CFTR/MRP), member 1; Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Synonyms: ABCC1, ABCC1p, hABCC1, ABCC1-001, ABCC1-002 ...