Disease-gene associations mined from literature

Literature associating TCF4 and diencephalic neoplasm

TCF4 [ENSP00000381382]

Class B basic helix-loop-helix protein 19; Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'; Basic helix-loop-helix proteins

Synonyms:  TCF4,  TCF4p,  hTCF4,  A0A024R2C0,  G0LNT1 ...

Linkouts:  STRING  Pharos  UniProt