Literature associating CABIN1 and focal segmental glomerulosclerosis
Calcineurin-binding protein cabin-1; May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes.
Synonyms: CABIN1, CABIN1p, hCABIN1, A0A024R1E5, B5MEB3 ...