DISEASES

Disease-gene associations mined from literature

Literature associating ROBO3 and bone structure disease

ROBO3 [ENSP00000380903]

Roundabout, axon guidance receptor, homolog 3 (Drosophila); Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal chord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1 (By similarity). Required for hindbrain axon midline crossing; Belongs to the immunoglobulin superfamily. ROBO family.

Synonyms:  ROBO3,  ROBO3p,  hROBO3,  A0A024R3L2,  A0A024R3M9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM