Disease-gene associations mined from literature

Literature associating PDCD1LG2 and type 1 diabetes mellitus 21

PDCD1LG2 [ENSP00000380855]

Programmed cell death 1 ligand 2; Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity); Belongs to the immunoglobulin superfamily. BTN/MOG family.

Synonyms:  PDCD1LG2,  Q9BQ51,  B7DC,  CD273,  PDCD1L2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM