Literature associating NOXO1 and lung mucoepidermoid carcinoma
SH3 and PX domain-containing protein 5; Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity.
Synonyms: NOXO1, NOXO1p, hNOXO1, H3BN18, Q8NFA2 ...