Disease-gene associations mined from literature

Literature associating NCF4 and autosomal recessive chronic granulomatous disease cytochrome b-positive type III

NCF4 [ENSP00000380334]

SH3 and PX domain-containing protein 4; Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex.

Synonyms:  NCF4,  NCF4p,  hNCF4,  NCF4-001,  NCF4-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM