DISEASES

Disease-gene associations mined from literature

Literature associating CCNF and frontotemporal dementia

CCNF [ENSP00000380256]

F-box only protein 1; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication; Belongs to the cyclin family. Cyclin AB subfamily.

Synonyms:  CCNF,  H0Y2P7,  P41002,  FBX1,  FBXO1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM