DISEASES

Disease-gene associations mined from literature

Literature associating KAT6A and Oropouche fever

KAT6A [ENSP00000380136]

Runt-related transcription factor-binding protein 2; Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML; MYST type domain containing lysine acetyltransferases

Synonyms:  KAT6A,  KAT6Ap,  hKAT6A,  A5PKX7,  A5PLL3 ...

Linkouts:  STRING  Pharos  UniProt