DISEASES

Disease-gene associations mined from literature

Literature associating SOX10 and cellular schwannoma

SOX10 [ENSP00000380093]

SRY (sex determining region Y)-box 10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3; SRY-boxes

Synonyms:  SOX10,  SOX10p,  hSOX10,  A0A024R1N6,  A6PVD3 ...

Linkouts:  STRING  Pharos  UniProt