Literature associating SOX10 and CHARGE syndrome
SRY (sex determining region Y)-box 10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3; SRY-boxes
Synonyms: SOX10, SOX10p, hSOX10, A0A024R1N6, A6PVD3 ...