DISEASES

Disease-gene associations mined from literature

Literature associating TMEM106B and frontotemporal dementia

TMEM106B [ENSP00000379901]

Transmembrane protein 106B; Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching; Belongs to the TMEM106 family.

Synonyms:  TMEM106B,  A0A024R9Z1,  C9J998,  C9JZ87,  F2Z3N7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM