DISEASES

Disease-gene associations mined from literature

Literature associating AP1S3 and pustulosis of palm and sole

AP1S3 [ENSP00000379891]

Clathrin assembly protein complex 1 sigma-1C small chain; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking.

Synonyms:  AP1S3,  AP1S3p,  hAP1S3,  B8ZZZ1,  C9JZK4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM