DISEASES

Disease-gene associations mined from literature

Literature associating ZNF143 and branchiootorenal syndrome 2

ZNF143 [ENSP00000379847]

Selenocysteine tRNA gene transcription-activating factor; Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8; Belongs to the GLI C2H2-type zinc-finger protein family.

Synonyms:  ZNF143,  ZNF143p,  hZNF143,  C9J2G7,  C9JCG1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM