Disease-gene associations mined from literature

Literature associating TSPO and cerebrovascular disease

TSPO [ENSP00000379563]

Peripheral-type benzodiazepine receptor; Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides; Belongs to the TspO/BZRP family.

Synonyms:  TSPO,  B1AH87,  B1AH88,  J3QLD3,  O76068 ...

Linkouts:  STRING  Pharos  UniProt