Disease-gene associations mined from literature

Literature associating MVP and testicular cancer

MVP [ENSP00000378760]

Major vault protein; Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

Synonyms:  MVP,  H3BNF2,  H3BNF6,  H3BP76,  H3BPZ2 ...

Linkouts:  STRING  Pharos  UniProt