Literature associating MMRN1 and blood platelet disease
Elastin microfibril interface located protein 4; Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein; EMI domain containing
Synonyms: MMRN1, MMRN1p, hMMRN1, E7EPG1, Q13201 ...