DISEASES

Disease-gene associations mined from literature

Literature associating MMRN1 and blood platelet disease

MMRN1 [ENSP00000378431]

Elastin microfibril interface located protein 4; Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein; EMI domain containing

Synonyms:  MMRN1,  MMRN1p,  hMMRN1,  E7EPG1,  Q13201 ...

Linkouts:  STRING  Pharos  UniProt