DISEASES

Disease-gene associations mined from literature

Literature associating GPT and severe pre-eclampsia

GPT [ENSP00000378408]

Glutamic-pyruvate transaminase (alanine aminotransferase); Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.

Synonyms:  GPT,  P24298,  AAT1,  GPT1,  P24298p ...

Linkouts:  STRING  Pharos  UniProt  OMIM