DISEASES

Disease-gene associations mined from literature

Literature associating PBRM1 and clear cell renal cell carcinoma

PBRM1 [ENSP00000378307]

BRG1-associated factor 180; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation; Bromodomain containing

Synonyms:  PBRM1,  PBRM1p,  hPBRM1,  C9J053,  C9J409 ...

Linkouts:  STRING  Pharos  UniProt  OMIM