Disease-gene associations mined from literature

Literature associating BAD and B-cell lymphoma

BAD [ENSP00000378040]

Bcl-xL/Bcl-2-associated death promoter; Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Synonyms:  BAD,  A0A024R562,  A8MXU7,  BAD-001,  BAD-002 ...

Linkouts:  STRING  Pharos  UniProt