Literature associating PPP2R2B and dentatorubral-pallidoluysian atrophy
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity).
Synonyms: PPP2R2B, PPP2R2Bp, hPPP2R2B, D6RB57, D6RF04 ...