DISEASES

Disease-gene associations mined from literature

Literature associating GPC3 and ovarian endodermal sinus tumor

GPC3 [ENSP00000377836]

Intestinal protein OCI-5; Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition; Glypicans

Synonyms:  GPC3,  GPC3p,  hGPC3,  I6QTG3,  P51654 ...

Linkouts:  STRING  Pharos  UniProt  OMIM