Literature associating GPC3 and nephroblastoma
GPC3 [ENSP00000377836]
Intestinal protein OCI-5; Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition; Glypicans
Synonyms: GPC3, GPC3p, hGPC3, I6QTG3, P51654 ...