Disease-gene associations mined from literature

Literature associating G3BP1 and mouth disease

G3BP1 [ENSP00000377681]

GTPase activating protein (SH3 domain) binding protein 1; May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium- dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA; RNA binding motif containing

Synonyms:  G3BP1,  G3BP1p,  hG3BP1,  DKFZP313K0921,  DKFZP686L1159 ...

Linkouts:  STRING  Pharos  UniProt