DISEASES

Disease-gene associations mined from literature

Literature associating FABP6 and acute vascular insufficiency of intestine

FABP6 [ENSP00000377549]

Intestinal bile acid-binding protein; Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Synonyms:  FABP6,  FABP6p,  hFABP6,  H0YB64,  I-BALB ...

Linkouts:  STRING  Pharos  UniProt  OMIM