DISEASES

Disease-gene associations mined from literature

Literature associating ARHGAP9 and ornithosis

ARHGAP9 [ENSP00000377380]

Rho-type GTPase-activating protein 9; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate; Pleckstrin homology domain containing

Synonyms:  ARHGAP9,  ARHGAP9p,  hARHGAP9,  F8VQR0,  F8VQY5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM