DISEASES

Disease-gene associations mined from literature

Literature associating PTPRZ1 and oligodendroglioma

PTPRZ1 [ENSP00000377047]

Protein tyrosine phosphatase, receptor-type, Z polypeptide 1; Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades (By similarity); Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.

Synonyms:  PTPRZ1,  PTPRZ1p,  hPTPRZ1,  P23471,  PTPRZ1-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM