DISEASES

Disease-gene associations mined from literature

Literature associating PDGFD and familiar ovarian carcinoma

PDGFD [ENSP00000376865]

Spinal cord-derived growth factor B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).

Synonyms:  PDGFD,  H0YD37,  Q9GZP0,  H0YD37p,  hH0YD37 ...

Linkouts:  STRING  Pharos  UniProt  OMIM