DISEASES

Disease-gene associations mined from literature

Literature associating POU2AF1 and methotrexate-associated lymphoproliferation

POU2AF1 [ENSP00000376786]

POU domain class 2-associating factor 1; Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers; Belongs to the POU2AF1 family.

Synonyms:  POU2AF1,  LOC101928620,  POU2AF1p,  hPOU2AF1,  E9PKH4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM