DISEASES

Disease-gene associations mined from literature

Literature associating SYCP3 and infertility

SYCP3 [ENSP00000376658]

Synaptonemal complex protein 3; Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells (By similarity). Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity); Belongs to the XLR/SYCP3 family.

Synonyms:  SYCP3,  SYCP3p,  hSYCP3,  A0A024RBF8,  Q8IZU3 ...

Linkouts:  STRING  Pharos  UniProt